Severe acute respiratory syndrome (SARS)-like WIV1-coronavirus (CoV) was first isolated\nfrom Rhinolophus sinicus bats and can use the human angiotensin converting enzyme 2 (ACE2) receptor.\nIn the current study, we investigate the ability of WIV1-CoV to infect Rousettus aegyptiacus bats. No\nclinical signs were observed throughout the experiment. Furthermore, only four oropharyngeal swabs\nand two respiratory tissues, isolated on day 3 post inoculation, were found positive for viral RNA.\nTwo out of twelve bats showed a modest increase in coronavirus specific antibodies post challenge.\nIn conclusion, WIV1-CoV was unable to cause a robust infection in Rousettus aegyptiacus bats.
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